Product Information
- Product Type
- Recombinant Protein
- Expression System
- E.coli
- Domain
- 1-917aa
- UniProt No.
- P19367
- NCBI Accession No.
- NP_000179.2
- Alternative names
- HK1, Hexokinase 1, EC 2.7.1.1, Hexokinase type I, HK I, Brain form hexokinase, Hexokinase-1, BB404130, dea, Glycolytic enzyme, HEXOKIN, Hexokinase PI, Hexokinase type I, Hexokinase, tumor isozyme, Hexokinase-A, HK1 tb, Hk1-s, HK1-ta, HK1-tc, HKI, HXK1, mHk1-s.
Product Specification
- Molecular Weight
- 104.6 kDa (937aa)
- Concentration
- 1mg/ml (determined by Bradford assay)
- Formulation
- Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
- Purity
- > 85% by SDS-PAGE
- Bioactivity
- Specific activity is > 8,000pmol/min/ug. One unit will convert 1pmole of D-Glucose to D-Glucose-6-phosphate per minute at pH 7.5 at 37C.
- Tag
- His-Tag
- Applications
- SDS-PAGE, Enzyme Activity
- Storage
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Data
SDS-PAGE
3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
Related Publications
-
Tsumura Y, et al. TMG-123, a novel glucokinase activator, exerts durable effects on hyperglycemia without increasing triglyceride in diabetic animal models. (PLoS One. 2017)
Yoshitake T, et al. Anti-Hexokinase 1 Antibody as a Novel Serum Biomarker of a Subgroup of Diabetic Macular Edema. (Sci Rep. 2019)
Note: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.