Product Information
- Product Type
- Domain
- N
- UniProt No.
- Recombinant Protein
- NCBI Accession No.
- ATGP7777
- Alternative names
- CD160, also known as CD160 antigen, is a human natural killer (NK) -cell-activating receptor that is also expressed on T-cell subsets. It is a tumor-specific antigen known to mediate cellular activation signals in CLL, and is a novel target for therapeutic manipulation and monitoring of minimal residual disease. It was identified as a T cell coinhibitory molecule that interacts with the herpesvirus entry mediator (HVEM) on antigen-presenting cells to deliver a potent inhibitory signal to CD4 (+) T cells. Recombinant human CD160, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Additional Information
- Immunology
Product Specification
- Molecular Weight
- Concentration
- CD160 antigen, CD160, BY55, NK1, NK28
- Formulation
- 0.25mg/ml (determined by absorbance at 280nm)
- Purity
- Farren TW., et al. (2011) Blood. 118:2174-2183.
- Bioactivity
- > 90% by SDS-PAGE
- Endotoxin
- 15.9 kDa (142aa)
- Tag
- Applications
- Storage
- f16 SDSPAGE Comment and Pic
Related Publications
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Note: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.