- Product Type
- Antigen Species
- NCBI Accession No.
- Alternative names
- AES-1, AES-2, ESP1, GRG, Grg-5, GRG5, TLE5
- RNA Reference Number
- OMIM Number
- Chromosome Location
- Store the plasmid at -20C.
- cDNA size
- Preparation before usage
- 1. Centrifuge at 7000rpm for 1 minute.
2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA.
Each tube contains approximately 10ug of lyophilized plasmid.
- Vector description:
- This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
- General Description
- Amino-terminal enhancer of split, also known AES, belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. This protein is expressed predominately in fetal brain, liver, lung, heart and kidney and in adult muscle. In addition, AES can repress NFkB-regulated gene expression and is thought to play an important role in initiating and maintaining cell differentiation events.
- Nucleotide Sequence:
ATGATGTTTC CACAAAGCAG GCATTCGGGC TCCTCGCACC TACCCCAGCA ACTCAAATTC ACCACCTCGG ACTCCTGCGA CCGCATCAAA GACGAATTTC AGCTACTGCA AGCTCAGTAC CACAGCCTCA AGCTCGAATG TGACAAGTTG GCCAGTGAGA AGTCAGAGAT GCAGCGTCAC TATGTGATGT ACTACGAGAT GTCCTACGGC TTGAACATCG AGATGCACAA ACAGGCTGAG ATCGTCAAAA GGCTGAACGG GATTTGTGCC CAGGTCCTGC CCTACCTCTC CCAAGAGCAC CAGCAGCAGG TCTTGGGAGC CATTGAGAGG GCCAAGCAGG TCACCGCTCC CGAGCTGAAC TCTATCATCC GACAGCAGCT CCAAGCCCAC CAGCTGTCCC AGCTGCAGGC CCTGGCCCTG CCCTTGACCC CACTACCCGT GGGGCTGCAG CCGCCTTCGC TGCCGGCGGT CAGCGCAGGC ACCGGCCTCC TCTCGCTGTC CGCGCTGGGT TCCCAGGCCC ACCTCTCCAA GGAAGACAAG AACGGGCACG ATGGTGACAC CCACCAGGAG GATGATGGCG AGAAGTCGGA TTAG
- Translation Sequence:
MMFPQSRHSG SSHLPQQLKF TTSDSCDRIK DEFQLLQAQY HSLKLECDKL ASEKSEMQRH YVMYYEMSYG LNIEMHKQAE IVKRLNGICA QVLPYLSQEH QQQVLGAIER AKQVTAPELN SIIRQQLQAH QLSQLQALAL PLTPLPVGLQ PPSLPAVSAG TGLLSLSALG SQAHLSKEDK NGHDGDTHQE DDGEKSD
Note: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.