Product Information
- Product Type
- cDNA
- Antigen Species
- Human
- NCBI Accession No.
- NP_060580.2
- Alternative names
- IRS-5, IRS5
- RNA Reference Number
- NM_018110.3
- OMIM Number
- 608333
- Chromosome Location
- 16q21
Product Specification
- Formulation
- Lyophilized
- Storage
- Store the plasmid at -20C.
- cDNA size
- 981bp
- Preparation before usage
- 1. Centrifuge at 7000rpm for 1 minute.
2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA.
Each tube contains approximately 10ug of lyophilized plasmid.
- Vector description:
- This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
- General Description
- DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.
Data
- Nucleotide Sequence:
ATGGCGACCAATTTCAGTGACATCGTCAAGCAAGGCTACGTGAAGATGAAGAGCAGGAAGCTCGGGATCTACCGGAGGTGCTGGCTGGTGTTCCGGAAATCCTCCAGCAAGGGGCCCCAGCGGCTGGAGAAGTATCCAGATGAGAAGTCGGTGTGCCTCCGGGGCTGCCCCAAGGTGACTGAGATCAGCAACGTCAAGTGTGTTACGCGGCTCCCCAAGGAGACCAAGCGGCAGGCGGTGGCCATCATATTCACTGATGACTCGGCACGTACCTTCACCTGCGACTCAGAGCTAGAGGCAGAGGAGTGGTACAAGACACTATCTGTGGAGTGTCTGGGGTCCCGCCTCAACGACATCAGTCTGGGAGAACCTGACCTCCTGGCCCCAGGGGTGCAGTGTGAACAGACAGATCGCTTCAATGTCTTCCTGCTGCCCTGCCCCAACCTGGACGTGTATGGCGAGTGCAAGCTGCAGATCACCCACGAGAACATCTACCTCTGGGACATCCACAACCCCCGTGTGAAGCTCGTCTCGTGGCCCCTCTGCTCACTGCGCCGCTATGGCCGGGATGCCACACGCTTTACCTTCGAGGCTGGCCGGATGTGTGATGCTGGGGAAGGACTCTATACCTTCCAGACACAAGAGGGGGAGCAGATTTACCAGCGCGTCCACAGTGCCACCCTGGCCATCGCAGAGCAGCACAAGCGGGTCCTGCTGGAAATGGAGAAGAACGTGAGGCTGCTGAACAAGGGCACGGAACATTACTCGTATCCCTGCACACCCACGACCATGCTGCCGCGCAGTGCCTACTGGCACCACATCACTGGTTCCCAGAACATCGCCGAAGCCTCCAGCTATGCTGGTGAGGGGTATGGGGCAGCCCAGGCCAGCTCGGAAACAGACCTCCTCAACAGATTCATCCTGCTAAAGCCAAAGCCCAGCCAGGGGGACAGCAGTGAGGCCAAGACCCCATCCCAGTGA - Translation Sequence:
MATNFSDIVK QGYVKMKSRK LGIYRRCWLV FRKSSSKGPQ RLEKYPDEKS VCLRGCPKVTEISNVKCVTR LPKETKRQAV AIIFTDDSAR TFTCDSELEA EEWYKTLSVE CLGSRLNDISLGEPDLLAPG VQCEQTDRFN VFLLPCPNLD VYGECKLQIT HENIYLWDIH NPRVKLVSWPLCSLRRYGRD ATRFTFEAGR MCDAGEGLYT FQTQEGEQIY QRVHSATLAI AEQHKRVLLEMEKNVRLLNK GTEHYSYPCT PTTMLPRSAY WHHITGSQNI AEASSYAGEG YGAAQASSETDLLNRFILLK PKPSQGDSSE AKTPSQ
Note: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.