- Product Type
- Recombinant Protein
- Expression System
- UniProt No.
- NCBI Accession No.
- Alternative names
- Tumor necrosis factor alpha, TNFA, TNFSF2, DIF (differentiation inducing factor ), CACHECTIN, DIF, TNF-alpha, Tumor necrosis factor alpha, Tumor necrosis factor alpha, TNF, tumor necrosis factor (TNF superfamily, member 2), TNF superfamily member 2,
- Molecular Weight
- 17.5 kDa (158aa) confirmed by MALDI-TOF
- 1mg/ml (determined by Bradford assay)
- Liquid in. Phosphate-Buffered Saline (pH 7.4)
- > 95% by SDS-PAGE
- Measured in a cytotoxicity assay using L-929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D. The ED50 range ≤ 0.2ng/ml.
- < 1 EU per 1ug of protein (determined by LAL method)
- SDS-PAGE, Bioactivity
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
Measured in a cytotoxicity assay using L-929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D. The ED50 range ≤ 0.2ng/ml.
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Yang SY, et al. NF-κB Activation and PPAR Transactivational Effects of a New Aliphatic Acid Amide from Pericarps of Zanthoxylum piperitum. (Bulletin of the Korean Chemical Society. 2014)
Sun YN, et al. NF-κB Inhibitory Activities of Phenolic and Lignan Components from the Stems of Acanthopanax divaricatus var. albeofructus. (The Korean Society of Pharmacognosy. 2014)
Sun YN, et al. Isolation and identification of chromone and pyrone constituents from Aloe and their anti-inflammatory activities. (Journal of Functional Foods. 2015)
Sun YN, et al. Nuclear Factor kappa B Activation and Peroxisome Proliferator-activated Receptor Transactivational Effects of Chemical Components of the Roots of Polygonum multiflorum. (Pharmacogn Mag. 2016)
Sun YN, et al. Nuclear Factor kappa B Activation and Peroxisome Proliferator-activated Receptor Transactivational Effects of Chemical Components of the Roots of Polygonum multiflorum. (Nat Prod Res. 2016)
Kwak MS, et al. A new phenolic derivative with soluble epoxide hydrolase and nuclear factor-kappaB inhibitory activity from the aqueous extract of Acacia catechu. (Redox Biol. 2019)
Note: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.