Product Information
- Product Type
- Recombinant Protein
- Expression System
- E.coli
- Domain
- 27-573aa
- UniProt No.
- P10809
- NCBI Accession No.
- NP_955472
- Alternative names
- 60 kDa heat shock protein mitochondrial, 60 kDa heat shock protein, mitochondrial, CPN60, GROEL, HLD4, HSP-60, HSP60, HSP65, HuCHA60, SPG13
Product Specification
- Molecular Weight
- 60 kDa (572aa)
- Concentration
- 0.5mg/ml (determined by Bradford assay)
- Formulation
- Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol
- Purity
- > 90% by SDS-PAGE
- Tag
- His-Tag
- Applications
- SDS-PAGE
- Storage
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Data
SDS-PAGE
3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
Related Publications
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Vilasi S,et al. Human Hsp60 with its mitochondrial import signal occurs in solution as heptamers and tetradecamers remarkably stable over a wide range of concentrations. (PLoS One. 2014)
Ricci C, et al. Stability and disassembly properties of human naïve Hsp60 and bacterial GroEL chaperonins. (Biophys Chem. 2016)
Ricci C, et al. Investigation on different chemical stability of mitochondrial Hsp60 and its precursor. (Biophys Chem. 2017)
Kaiser F, et al. Association between circulating levels of heat-shock protein 27 and aggressive periodontitis. (Cell Stress Chaperones. 2018)
Marino C, et al. Hsp60 Protects against Amyloid β Oligomer Synaptic Toxicity via Modification of Toxic Oligomer Conformation. (ACS Chem Neurosci. 2019)
Vilasi S, et al. Inhibition of Aβ 1-42 Fibrillation by Chaperonins: Human Hsp60 Is a Stronger Inhibitor than Its Bacterial Homologue GroEL. ACS Chem Neurosci. 2019)
Note: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.