NKMAX

Product Information

Product Type

cDNA

Antigen Species

Human

NCBI Accession No.

NP_001137467.1

Alternative names

LDPL

RNA Reference Number

NM_001143995.2

OMIM Number

605390

Chromosome Location

11q12.1

Product Specification

Formulation

Lyophilized

Storage

Store the plasmid at -20C.

cDNA size

1176bp

Preparation before usage

1. Centrifuge at 7000rpm for 1 minute.
2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA.
Each tube contains approximately 10ug of lyophilized plasmid.

Vector description:

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.

General Description

The product encoded by LPXN is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Data

1. Nucleotide Sequence:
   

   ATGTCTACATTATTGATCTCGTCTTCCGATGCCTTATTGGAGGAACTGGAACGCTCCACCCTTCAGGACAGTGATGAATATTCCAACCCAGCTCCTCTTCCCCTGGATCAGCATTCCAGAAAGGAGACTAACCTTGATGAGACTTCGGAGATCCTTTCTATTCAGGATAACACAAGTCCCTTGCCGGCGCAGCTCGTGTATACTACCAATATCCAGGAGCTCAATGTCTACAGTGAAGCCCAAGAGCCAAAGGAATCACCACCACCTTCTAAAACGTCAGCAGCTGCTCAGTTGGATGAGCTCATGGCTCACCTGACTGAGATGCAGGCCAAGGTTGCAGTGAGAGCAGATGCTGGCAAGAAGCACTTACCAGACAAGCAGGATCACAAGGCCTCCCTGGACTCAATGCTTGGGGGTCTGGAGCAGGAATTGCAGGACCTTGGCATTGCCACAGTGCCCAAGGGCCATTGTGCATCCTGCCAGAAACCGATTGCTGGGAAGGTGATCCATGCTCTAGGGCAATCATGGCATCCTGAGCATTTTGTCTGTACTCATTGCAAAGAAGAGATTGGCTCCAGTCCCTTCTTTGAGCGGAGTGGCTTGGCCTACTGCCCCAACGACTACCACCAACTTTTTTCTCCACGCTGTGCTTACTGCGCTGCTCCCATCCTGGATAAAGTGCTGACAGCAATGAACCAGACCTGGCACCCAGAGCACTTCTTCTGCTCTCACTGCGGAGAGGTGTTTGGTGCAGAAGGCTTTCATGAGAAGGACAAGAAGCCATATTGCCGAAAGGATTTCTTAGCCATGTTCTCACCCAAGTGTGGTGGCTGCAATCGCCCAGTGTTGGAAAACTACCTTTCAGCCATGGACACTGTCTGGCACCCAGAGTGCTTTGTTTGTGGGGACTGCTTCACCAGTTTTTCTACTGGCTCCTTCTTTGAACTGGATGGACGTCCATTCTGTGAGCTCCATTACCATCACCGCCGGGGAACGCTCTGCCATGGGTGTGGGCAGCCCATCACTGGCCGTTGTATCAGTGCCATGGGGTACAAGTTCCATCCTGAGCACTTTGTGTGTGCTTTCTGCCTGACACAGTTGTCGAAGGGCATTTTCAGGGAGCAGAATGACAAGACCTATTGTCAACCTTGCTTCAATAAGCTCTTCCCACTGTAA

2. Translation Sequence:
   MSTLLISSSD ALLEELERST LQDSDEYSNP APLPLDQHSR KETNLDETSE ILSIQDNTSP LPAQLVYTTN IQELNVYSEA QEPKESPPPS KTSAAAQLDE LMAHLTEMQA KVAVRADAGK KHLPDKQDHK ASLDSMLGGL EQELQDLGIA TVPKGHCASC QKPIAGKVIH ALGQSWHPEH FVCTHCKEEI GSSPFFERSG LAYCPNDYHQ LFSPRCAYCA APILDKVLTA MNQTWHPEHF FCSHCGEVFG AEGFHEKDKK PYCRKDFLAM FSPKCGGCNR PVLENYLSAM DTVWHPECFV CGDCFTSFST GSFFELDGRP FCELHYHHRR GTLCHGCGQP ITGRCISAMG YKFHPEHFVC AFCLTQLSKG IFREQNDKTY CQPCFNKLFP L