Product Information
- Product Type
- Recombinant Protein
- Expression System
- E.coli
- Domain
- 1-140aa
- UniProt No.
- P37840
- NCBI Accession No.
- NP_000336.1
- Alternative names
- SNCA, NACP, PARK1, PARK4, PD1, α-synuclein Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, Parkinson disease 4, autosomal dominant Lewy body
Product Specification
- Molecular Weight
- 14.4 kDa (140aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
- Concentration
- 1mg/ml (determined by BCA assay)
- Formulation
- Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 0.1M NaCl
- Purity
- > 95% by SDS-PAGE
- Tag
- Non-Tagged
- Applications
- SDS-PAGE
- Storage
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Data
SDS-PAGE
3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
Related Publications
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Park JY, et al. Microglial phagocytosis is enhanced by monomeric alpha-synuclein, not aggregated alpha-synuclein: implications for Parkinsons disease. (Glia. 2008)
Kim KS, et al. Proteolytic cleavage of extracellular α-synuclein by plasmin: implications for Parkinson disease. (J Biol Chem. 2012)
Konno M, et al. Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy. (Mol Neurodegener. 2012)
Note: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.