Product Information
- Product Type
- Recombinant Protein
- Expression System
- E.coli
- Domain
- 51-271aa
- UniProt No.
- P21964
- NCBI Accession No.
- NP_000745.1
- Alternative names
- Catechol-O-methyltransferase, COMT
Product Specification
- Molecular Weight
- 24.4 kDa (221aa) confirmed by MALDI-TOF
- Concentration
- 1mg/ml (determined by Bradford assay)
- Formulation
- Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM MgCl2, 10% glycerol
- Purity
- > 95% by SDS-PAGE
- Endotoxin
- < 1 EU per 1ug of protein (determined by LAL method)
- Tag
- Non-Tagged
- Applications
- SDS-PAGE
- Storage
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Data
SDS-PAGE
3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
Related Publications
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Ishida Y, et al. Yokukansan, a Traditional Japanese Medicine, Enhances the L-DOPA-Induced Rotational Response in 6-Hydroxydopamine-Lesioned Rats: Possible Inhibition of COMT. (Biol Pharm Bull. 2016)
Ikeda M, et al. Inhibitory Effect of Bovine Lactoferrin on Catechol-O-Methyltransferase. (Molecules. 2017)
Ikeda M, et al. Effects of bovine lactoferrin on l-DOPA absorption and metabolism in mice. (Food Funct. 2018)
Nagai M, et al. Comparative examination of levodopa pharmacokinetics during simultaneous administration with lactoferrin in healthy subjects and the relationship between lipids and COMT inhibitory activity in vitro. (Nutr Neurosci. 2020)
Note: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.