Product Information
- Product Type
- Recombinant Protein
- Expression System
- Baculovirus
- Domain
- 36-161aa
- UniProt No.
- P16410
- NCBI Accession No.
- NP_005205
- Alternative names
- Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, CELIAC3, Celiac disease 3, Insulin-dependent diabetes mellitus 12, IDDM12, CD, GSE
- Additional Information
- ATGP3364 has been replaced with a catalog number ATGP3914.
Product Specification
- Molecular Weight
- 40.8 kDa (368aa)
- Concentration
- 0.5mg/ml (determined by absorbance at 280nm)
- Formulation
- Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
- Purity
- > 95% by SDS-PAGE
- Bioactivity
- The activity is determined by the IL-2 ELISA in a using Jurkat human acute T cell leukemia cells. The ED50 range ≤150ng/ml with Human B7 1/CD80.
- Endotoxin
- < 1 EU per 1ug of protein (determined by LAL method)
- Tag
- hIgG-His-Tag
- Applications
- SDS-PAGE, Bioactivity
- Storage
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Data
SDS-PAGE
3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
Biological Activity
Human CTLA-4 inhibits Human B7 1/CD80 induced IL-2 secretion of the Jurkat human acute T cell leukemia cells. The ED50 range ≤150 ng/ml.
Note: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.