NKMAX

Product Information

Product Type

cDNA

Antigen Species

Human

NCBI Accession No.

NP_005089.2

Alternative names

ABF-1, ABF1, bHLHa22, MYOR

RNA Reference Number

NM_005098.3

OMIM Number

603628

Chromosome Location

8q21

Product Specification

Formulation

Lyophilized

Storage

Store the plasmid at -20C.

cDNA size

621bp

Preparation before usage

1. Centrifuge at 7000rpm for 1 minute.
2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA.
Each tube contains approximately 10ug of lyophilized plasmid.

Vector description:

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.

General Description

This gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway.

Data

1. Nucleotide Sequence:
   

   ATGTCCACGG GCTCGGTGAG TGATCCGGAG GAGATGGAGC TTCGGGGGCT GCAGCGGGAG TACCCGGTCC CCGCCTCCAA GAGGCCGCCC CTCCGCGGCG TAGAGCGCAG CTACGCCTCG CCCAGTGACA ACTCGTCGGC AGAGGAGGAG GACCCCGACG GCGAGGAGGA GCGCTGCGCT CTGGGCACAG CCGGCAGCGC GGAAGGCTGC AAGAGGAAGC GGCCCCGTGT GGCTGGGGGC GGCGGCGCAG GTGGTAGCGC GGGCGGTGGT GGCAAGAAGC CCCTCCCGGC CAAGGGCTCA GCCGCAGAGT GCAAGCAGTC GCAGCGGAAC GCGGCCAACG CCCGTGAGCG TGCCCGGATG CGCGTGCTGA GCAAAGCCTT CTCCAGGCTC AAGACCAGCC TGCCCTGGGT GCCCCCCGAC ACTAAGCTCT CCAAGCTGGA CACGCTCCGG CTGGCTTCCA GTTACATCGC TCACCTGCGG CAGCTGTTGC AGGAGGACCG CTATGAGAAC GGCTACGTGC ACCCAGTGAA CCTGACATGG CCATTCGTGG TCTCGGGAAG ACCGGACTCT GACACCAAAG AAGTTTCCGC AGCCAACAGA CTATGTGGAA CCACCGCTTA A

2. Translation Sequence:
   MSTGSVSDPE EMELRGLQRE YPVPASKRPP LRGVERSYAS PSDNSSAEEE DPDGEEERCA LGTAGSAEGC KRKRPRVAGG GGAGGSAGGG GKKPLPAKGS AAECKQSQRN AANARERARM RVLSKAFSRL KTSLPWVPPD TKLSKLDTLR LASSYIAHLR QLLQEDRYEN GYVHPVNLTW PFVVSGRPDS DTKEVSAANR LCGTTA