NKMAX

Product Information

Product Type

cDNA

Antigen Species

Human

NCBI Accession No.

NP_004115.1

Alternative names

GMF

RNA Reference Number

NM_004124.2

OMIM Number

601713

Chromosome Location

14q22.2

Product Specification

Formulation

Lyophilized

Storage

Store the plasmid at -20C.

cDNA size

429bp

Preparation before usage

1. Centrifuge at 7000rpm for 1 minute.
2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA.
Each tube contains approximately 10ug of lyophilized plasmid.

Vector description:

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.

General Description

GMFB, also known as GMF, belongs to the GMF subfamily of the larger actin-binding protein ADF family. This protein, which is phosphorylated following phorbol ester stimulation, is important for the nervous system. It causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. Overexpression of GMFB in astrocytes has been shown to enhance brain-derived neurotrohic factor (BDNF) production. GMFB expression is increased by exercise, and the protein is crucial for exercise-induction of BDNF.

Data

1. Nucleotide Sequence:
   

   ATGAGTGAGT CTTTGGTTGT TTGTGATGTT GCCGAAGATT TAGTGGAAAA GCTGAGAAAG TTTCGTTTTC GCAAAGAAAC GAACAACGCT GCTATTATAA TGAAGATTGA CAAGGATAAA CGCCTGGTGG TACTGGATGA GGAGCTTGAG GGCATTTCAC CAGATGAACT TAAAGATGAA CTACCTGAAC GACAACCTCG CTTCATTGTG TATAGTTATA AATATCAACA TGATGATGGA AGAGTTTCAT ATCCTCTGTG CTTTATTTTC TCCAGTCCTG TTGGATGTAA GCCTGAACAA CAGATGATGT ATGCTGGAAG TAAGAATAAG CTAGTCCAGA CAGCTGAACT AACCAAGGTA TTTGAAATAA GAAATACCGA AGACCTAACT GAAGAATGGT TACGTGAGAA ACTTGGATTT TTTCACTAA

2. Translation Sequence:
   MSESLVVCDV AEDLVEKLRK FRFRKETNNA AIIMKIDKDK RLVVLDEELE GISPDELKDE LPERQPRFIV YSYKYQHDDG RVSYPLCFIF SSPVGCKPEQ QMMYAGSKNK LVQTAELTKV FEIRNTEDLT EEWLREKLGF FH