Product Information
- Product Type
- Recombinant Protein
- Expression System
- Baculovirus
- Domain
- 20-365aa
- UniProt No.
- P08887
- NCBI Accession No.
- NP_000556
- Alternative names
- Interleukin-6 receptor subunit alpha, IL-6 receptor subunit alpha, IL-6R subunit alpha, IL-6R 1, Membrane glycoprotein 80, gp80, CD126
- Additional Information
- ATGP3819 has been replaced with a catalog number ATGP3919.
Product Specification
- Molecular Weight
- 39.6 kDa (355aa)
- Concentration
- 0.25mg/ml (determined by absorbance at 280nm)
- Formulation
- Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
- Purity
- > 90% by SDS-PAGE
- Bioactivity
- Measured by its ability to inhibit proliferation using M1 mouse myeloid leukemia cells. The ED50 range ≤20ng/ml with Human IL-6.
- Endotoxin
- < 1 EU per 1ug of protein (determined by LAL method)
- Tag
- His-Tag
- Applications
- SDS-PAGE, Bioactivity
- Storage
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Data
SDS-PAGE
3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
Biological Activity
Human IL-6 R alpha inhibits Human IL-6 induced cell proliferation in the M1 mouse myeloid leukemia cells. The ED50 range ≤20 ng/ml.
Note: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.