Product Information
- Product Type
- Recombinant Protein
- Expression System
- E.coli
- Domain
- 1-140aa
- UniProt No.
- P37840
- NCBI Accession No.
- NP_000336
- Alternative names
- SNCA, NACP, PARK1, alpha-Synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, Alpha synuclein, Alpha-synuclein isoform NACP140, alphaSYN, MGC105443, MGC110988, MGC127560, MGC64356, Non A beta component of AD amyloid, Non A4 component of amyloid precursor, Non-A-beta component of alzheimers disease amyloid, precursor of PARK 1, PARK 4, PARK4, Parkinson disease familial 1, PD 1, PD1, Synuclein alpha,
Product Specification
- Molecular Weight
- 14.4 kDa (140aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
- Concentration
- 1mg/ml (determined by BCA assay)
- Formulation
- Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 0.1 M NaCl, 1mM MgCl2
- Purity
- > 95% by SDS-PAGE
- Endotoxin
- < 1 EU per 1ug of protein (determined by LAL method)
- Tag
- Non-Tagged
- Applications
- SDS-PAGE
- Storage
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Data
SDS-PAGE
3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain. ..
Related Publications
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Lee HJ, et al. Direct Transfer of a-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies. J Biol Chem. 2010 Mar 19;285(12):9262-72.
Kim KS, et al. Regulation of Weibel-Palade Body Exocytosis by a-Synuclein in Endothelial Cells. J Biol Chem. 2010 Jul 9;285(28):21416-25.
Rodriguez-Araujo G, et al. Low alpha-synuclein levels in the blood are associated with insulin resistance. Sci Rep. 2015 Jul 10;5:12081.
Note: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.